Amniotic Membrane Market: Significance & Global Performance

Amniotic membrane or amnion, a thin membrane on the inner side of the fetal placenta and composed of the epithelium, has emerged as an ideal source for tissue transplantation. Moreover, amnion has an array of biological properties, making it attractive for use in various surgical procedures, including ocular surface reconstruction and tissue engineering.

The advancements in anatomy have triggered significant investments in research and development of amniotic membrane applications. While AM has shown beneficial results in burn injuries, the upsurge in R&D investments has increased its use in eye surgery, cell therapy, stem cell research, and more, boosting the amniotic membrane market growth prospects.

In fact, the identification of new stem cells has increased the membrane’s potential, making it ideal for developing regenerative medicines. For instance, Organogenesis Holdings Inc, a leading regenerative medicine company, gained approval from the US FDA for ReNu, a cryopreserved amniotic suspension allograft, to manage symptoms related to knee osteoarthritis.



Amniotic Membrane Market - Global & Regional Trends

As per estimates, the global amniotic membrane market will display revenue growth at a CAGR of 7.01% during the forecast period 2022-2028.

Considering the evolving healthcare sector, the amniotic membrane market is expected to witness tremendous growth in the Asia-Pacific nations. Estimates suggest that approximately half a billion people in the region will be 65 or older by 2025. This change in demographics, in addition to a shift in consumer expectations, will widen the market’s scope. In this regard, the growing demand for chronic care management will expand amnion application in ophthalmology, burn injuries, and cosmetic surgeries, among others.

Additionally, amniotic membrane transplantation has gained momentum in various conjunctival and corneal diseases, signaling opportunistic growth for players in the APAC region. Considering its growth in North America, amnions have proven advantageous in treating limbal stem cell deficiency, providing support and protection to transplanted limbal tissues and stem cells. Recently, in Canada, numerous techniques have been developed to dehydrate amnion while preserving the wound-healing properties to formulate a temperature-stable allograft.

Furthermore, the United Kingdom is the center of research and development of amniotic membrane applications in Europe. Several hospitals, such as NuVision, have gained expertise in providing AM treatments. Amniotic membrane treatments are gaining center stage across the nation, given the technological advancements. For instance, in November 2021, several ophthalmologists shared their innovations of AM application in treating ocular surface conditions through a webinar sponsored by NuVision Biotherapies Ltd.

Market by Application – Expert Outlook

  • Surgical Wounds: Human amniotic membrane has been used for treating acute and chronic wounds, decreasing infection and pain while accelerating the healing time. The surgical wound segment dominates the overall market and is expected to maintain its stronghold till 2028. Although a plethora of wound dressings are available, chronic wounds remain a major medical concern. As a result, chronic wounds awareness programs largely support amnion application. For instance, the Wound Healing and Hyperbaric Center at Carteret Health Care, a Healogic Network member, is engaged in raising awareness of chronic wounds, providing advanced therapies.

  • Ophthalmology: The rise in chronic and infectious diseases has resulted in a global rise in surgeries, boosting the market’s potential. Amniotic membrane is rapidly used in ophthalmic surgeries to initiate faster recovery and decrease inflammation. Amnion has become crucial in eye treatments, given its anti-scarring and anti-inflammatory properties. For instance, Bio Tissue Inc offers AmnioGraft to treat ocular surface indications like corneal ulcers, dry eye, chemical burns, etc. Besides, AM is highly preferred in developing regions since it is cheaper than allografts.

Competitive Analysis

For any company, acquisitions and agreements ensure expansion in business footings. Acquisitions, for instance, are quicker, cheaper, and less risky compared to other methods to extend volume sales. On the other hand, agreements are crucial to eliminating disagreements, confusion, or changes that may transpire during the course of the business period.


Notable acquisitions and agreements that support the market’s development:

  • In February 2021, Katena Products Inc, a leading provider of premium ophthalmic instruments and devices, announced the acquisition of ASICO LLC to expand the ophthalmic surgical product line and lead in the innovation of new products.

  • Integra LifeSciences Corporation, in January 2021, acquired ACell Inc and its proprietary MatriStem UMB to offer comprehensive wound management solutions.

  • Celularity Inc and Oncternal Therapeutics Inc entered into a research partnership in September 2021 to examine placental-derived cellular treatments.

  • Celularity also collaborated with Imugene Ltd in August 2021 to employ Imugene’s CD19 oncolytic virus technology and its CD19 CYCART-19 to remedy solid tumors.

In Conclusion,

The amniotic membrane market has shown rapid and promising results in healing damaged tissues. From chemical burns to ulcers to the cornea, amnions have emerged as suitable membranes in wound care management. This indicates that the use of AM in medicine and therapies is expanding in various branches of medicine.

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